Peptides have become a buzzword in the world of health, fitness, and biohacking—and for good reason. In 2025, the science behind weight loss peptides has advanced significantly, offering safer and more targeted options for those looking to burn fat, regulate appetite, and improve metabolic health. If you’re in Canada and exploring peptides for fat loss, this guide will walk you through the top contenders—backed by research and trusted by the community.
Peptides are short chains of amino acids that signal the body to perform specific functions—like releasing growth hormone, reducing appetite, or burning fat. Unlike generic weight loss supplements, peptides work on a cellular level to encourage biological processes that support sustainable fat loss.
Most peptides used for fat loss—like BPC-157, CJC-1295, or semaglutide—are considered legal for research purposes in Canada. However, they are not approved by Health Canada for over-the-counter therapeutic use. Always consult a medical professional and ensure your source is reputable and lab-tested.
Function: Appetite suppression, blood sugar regulation
Why it works: Originally developed for diabetes, Semaglutide is now globally recognized for its powerful appetite-reducing effects. It mimics the GLP-1 hormone, which signals fullness to the brain.
Clinical Support: Multiple studies show 10–15% body weight loss over 6 months with controlled Semaglutide usage.
Function: Growth hormone release, fat metabolism
Why it works: CJC-1295 stimulates your body’s natural growth hormone, which supports fat burning, muscle retention, and improved recovery. With DAC (Drug Affinity Complex), it remains active longer in the bloodstream.
Best for: Night-time fat burning and fitness-focused users.
Stackable with: Ipamorelin
Function: Stimulates GH release without increasing cortisol
Why it works: Unlike older peptides (like GHRP-6), Ipamorelin targets growth hormone without the hunger-inducing or stress-related side effects.
Popular Stack: CJC-1295 + Ipamorelin = powerful GH synergy
Use case: Ideal for beginners aiming for steady, safe fat reduction.
Function: Targets stored fat, especially abdominal fat
Why it works: AOD 9604 is a modified fragment of HGH (Human Growth Hormone) specifically designed for lipolysis (fat breakdown), without the side effects of full HGH.
Bonus: No significant impact on insulin levels or IGF-1.
Ideal for: Stubborn fat, especially in older adults.
Function: Tissue healing, gut health, inflammation control
Why it works: While not a direct fat-burner, BPC-157 supports gut lining repair, digestion, and recovery from workouts—all essential for a healthy metabolism.
Fun Fact: Many users report better nutrient absorption and reduced bloating, leading to indirect fat loss benefits.
Weight loss isn’t just about calorie restriction or crash diets. With the right research peptides, your body can be gently guided to perform more efficiently—burning fat, managing hunger, and preserving lean muscle.
At PHX Labs, we provide high-purity, lab-tested peptides for research purposes in Canada, backed by third-party testing and Canadian-based shipping.
👉 Browse Weight Loss Peptides at PHX Labs
👉 Learn more about BPC-157 in Canada
👉 Use our Peptide Dosage Calculator
