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The Anti-Aging Stack: Collagen, Peptides & NAD+ in One Routine

Aging is inevitable—but looking and feeling your best while aging? That’s where science is catching up. In 2025, more Canadians are turning to anti-aging stacks that combine collagen, peptides, and NAD+ to support energy, skin health, cognitive clarity, and recovery.
In this guide, we’ll break down how each of these ingredients works, how they complement each other, and how to incorporate them into a simple, research-backed routine.
Why Stack for Anti-Aging?
The aging process isn’t controlled by one system—it’s a combination of:
- Collagen breakdown (leading to wrinkles, sagging skin)
- Mitochondrial decline (resulting in fatigue, slower recovery)
- Hormonal changes (impacting mood, energy, and libido)
- Cellular damage (from oxidative stress and inflammation)
Using a targeted stack of peptides, collagen, and NAD+ precursors addresses aging from multiple angles—internally and externally.
Collagen: The Structural Foundation
What It Is:
Collagen is the most abundant protein in the body, making up skin, joints, and connective tissue.
What It Does in Anti-Aging:
- Improves skin hydration and elasticity
- Reduces wrinkle depth
- Supports joint and ligament health
- Enhances hair and nail strength
How to Use:
Hydrolyzed collagen peptides (like type I and III) are ideal for absorption. Pair with Vitamin C for improved synthesis.
Peptides: Cellular Communicators
What They Are:
Peptides are short chains of amino acids that signal cellular processes such as regeneration, hormone release, and tissue repair.
Anti-Aging Peptides to Know:
- GHK-Cu (Copper Peptide): Stimulates collagen production and skin regeneration
- CJC-1295 + Ipamorelin: Supports natural growth hormone release, enhancing muscle tone, sleep, and fat metabolism
- BPC-157: Assists in tissue healing and inflammation reduction
Benefits in Aging:
- Firmer, younger-looking skin
- Better sleep and recovery
- Reduction in joint pain and inflammation
How to Use:
Peptides are available for research use only in Canada and should be sourced from a lab offering COAs and verified purity.
NAD+: The Energy Molecule
What It Is:
NAD+ (Nicotinamide Adenine Dinucleotide) is a coenzyme found in every cell, critical for energy metabolism and DNA repair.
Why It Declines:
By age 40, NAD+ levels can drop by 50%. This decline is linked to:
- Fatigue
- Slower metabolism
- Cognitive decline
- Skin dullness
How to Replenish:
- NAD+ precursors like NMN or NR (Nicotinamide Riboside)
- Shown in studies to boost mitochondrial function and support healthy aging
Bonus:
NAD+ also enhances the effects of certain peptides, improving cellular response and recovery.
Suggested Anti-Aging Stack Routine
Time | Supplement | Benefit |
---|---|---|
Morning | Collagen Peptides + Vitamin C | Skin, joints, gut health |
Midday | NAD+ precursor (e.g., NMN) | Energy, cognitive support |
Evening | CJC-1295 + Ipamorelin (research) | GH boost, anti-aging, recovery |
Topical | GHK-Cu Serum | Skin repair, wrinkle reduction |
Is It Legal in Canada?
- Collagen & NAD+ precursors are legal and widely available in supplement form.
- Peptides like CJC-1295 or GHK-Cu are legal for research purposes only in Canada.
Always purchase from verified labs like PHX Labs with transparent sourcing and lab-tested quality.
Final Thoughts
The anti-aging approach of 2025 is no longer about quick fixes or miracle creams. It’s about layering smart, synergistic ingredients like collagen, peptides, and NAD+ to support your body’s natural renewal processes.
PHX Labs offers research-grade beauty peptides in Canada shipped Canada-wide—trusted by wellness professionals and researchers seeking real results.